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'Omic Technologies and Resources will introduce a range of molecular biology, genetic engineering and bioinformatic techniques (e.g., gene cloning, engineering alterations in a gene, screening for genes, genome mapping, sequencing and editing projects), and illustrate how these can be, and have been, applied and adapted to answer major questions in the biological sciences and medical genetics.

BIOL21152 Pre-requisite is BIOL10221

BIOL21152 Pre- & Co-requisites are BIOL10221

This unit will introduce a range of molecular biology, genetic engineering and bioinformatic techniques and illustrate how these can be, and have been, applied and adapted to answer major questions in the biological sciences and medical genetics. Using a topical example-driven approach - including human, animal, plant and micro-organismal - students will be exposed to a number of the important techniques that underpin many of the recent advances in understanding biological systems at the molecular level. Examples will be used to explain the step change that occurs between the analysis of single genes, proteins etc. and the analysis of most, or all, of the genes, proteins and metabolites within an organism. In addition, students will gain an understanding of the cross-talk and interactions that occur between different genes and gene products.

Upon completion of this unit, students will gain an understanding of:

• Gene cloning, engineering alterations in a gene, screening for genes.
• Genome mapping and sequencing projects.
• Manipulating DNA in vitro and genomes in vivo.
• Transcriptomics approaches.
• How proteins can be made and manipulated.
• Using single-celled organisms, plants and animals as experimental models.
• Dealing with large-scale datasets generated from ’omic scale experiments.

 

• Analysis of individual genes
• Analysis of genomes (transcriptomics)
• Understanding gene function (proteomics)
• Analysis of small molecules (metabolomics)
• Understanding the integration of the above (systems biology)

 

The written exam is one problem-based question (50% of exam) and one essay from a choice (50% of exam). Weekly online multiple choice exercises make up 20% of the overall mark.

Students will receive feedback via the Canvas module for this unit, which forms part of the continuous assessment of the unit. Students will also be afforded the opportunity to receive written feedback on an examination-style essay and a series of examination-style short-answer questions.

• Brown, TA (2017) Genomes (4^th edition). Garland Science - recommended

The year studying abroad is an integral part of the course and must be completed. Some costs, such as tuition fees, are substantially lower. Other costs can vary and are not included in the tuition fee. For example, living costs may be higher or lower than the UK, and there are travel-related costs to consider, such as paying for a passport, visa fees, health insurance, and (if needed) vaccinations.

All students should normally be able to complete their programme of study without incurring additional study costs over and above the tuition fee for that programme. Any unavoidable additional compulsory costs totalling more than 1% of the annual home undergraduate fee per annum, regardless of whether the programme in question is undergraduate or postgraduate taught, will be made clear to you at the point of application. Further information can be found in the University's (PDF document, 91KB).

Students participating in placements outside the UK may be able to apply for funding from the depending on eligibility. Priority will be given to students from low income households.